GPS-Prot: A web-based visualization platform for integrating host-pathogen interaction data
Melanie Bennett Brewer is the coordinator for the HARC Center at the UCSF, where she works on web-based systems to integrate and visualize host-pathogen data, using HIV as a model system. She received a Ph.D. degree in Molecular Biology from UCLA in 1993, where she studied the crystallographic structures of diphtheria toxin and first described the phenomenon of “3D domain swapping”, a paradigm for protein assembly that has now been observed in many other systems. Previously, she was a postdoctoral fellow at Caltech, where she studied protein assemblies involved in the iron-storage disorder hereditary hemochromatosis and in Huntington’s disease. Her interests include protein-protein interactions as they relate to normal cellular functioning and pathogenesis and development of systems to integrate and visualize that data.