A Ligand for Every target; A target for Every Ligand.
John Irwin is an Adjunct Professor at the University of California Department of Pharmaceutical Chemistry. He develops computational tools and databases to enable research in pharmacology and chemical biology. He is best known for ZINC, a database of commercially available compounds for virtual screening, zinc15.docking.org, the Similarity Ensemble Approach, a method to predict the biological targets of small molecules, sea16.docking.org, DUDE, a benchmark for molecular docking, dude.docking.org and DOCK Blaster, a web-based molecular docking system, blaster.docking.org. He uses these tools in collaborations to discover new chemical matter for biology.