Large-Scale Analysis of Biological and Chemical Data

Wednesday, March 15, 2006 - 17:30
TH 331
Yimeng Dou, University of California - Irvine

Alternative splicing changed the “the "one-gene-one-protein" view. One pre-mRNA can make different mRNAs and lead to various ripe proteins. I will introduce the large-scale data mining of alternative splicing machinery in several genomes and the progress we made in this field, such as in the link between AS events and intron length, Nonsense Mediated Decay, and distinct patterns of splice site usage.

I will also present the UCI ChemDB, one of the largest free chemical databases in the world, its emphasis on being useful for virtual drug docking, and its unique features such as reaction processing.


Yimeng Dou received her B.S. from Nanjing University , China in 2001. She continued on as a graduate student at the University of California , Irvine under the guidance of Professor Pierre Baldi. She will receive her Ph.D. in Computer Science with a specific concentration in Informatics in Biology and Medicine in June 2006. Yimeng is a member of the Institute for Genomics and Bioinformatics and the Center for Complex Biological Systems at UC Irvine. She is also a Bioinformatics consultant for a Laguna Hills based biotechnology company, Coda Genomics, Inc.